Ann. occup. Hyg., Vol. 46, No. 7, pp. 563-574, 2002
© 2002 British Occupational Hygiene Society
Published by Oxford University Press
Asthma and Work
The Colt Lecture, delivered at the Ninth International Symposium on Inhaled Particles, Cambridge, September 2001
Department of Occupational and Environmental Medicine, Imperial College, Emmanuel Kaye Building, Manresa Road, London SW3 6LR, UK
Received 13 June 2002; in final form 13 June 2002
| The first 150 words of the full text of this article appear below. |
| INTRODUCTION |
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It is a great privilege to be invited to deliver the Colt lecture. The Colt Foundation, which this lecture honours, was founded by the OHea family to support research with the aim of reducing ill health caused by work. Their contribution provides the major charitable source of funding in the UK for investigator-initiated research into the causes and consequences of occupational disease. It is a pleasure in giving this lecture to give public recognition to the OHea family for their unwavering commitment to occupational health research.
I have chosen to focus on asthma and work, not only because this has been a major research interest of mine for more than two decades but, of more importance, because asthma is the most prevalent cause in the UK, and probably in the Western World, of respiratory ill health during working life. Now recognized as a chronic inflammatory disease of the bronchial airways,
| THE NATURE OF ASTHMA: INCITERS AND INDUCERS |
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| ASTHMA IN WORKING LIFE |
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| THE INTER-RELATIONSHIP OF ASTHMA AND WORK |
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| ASTHMA INDUCED BY WORK |
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| ESTIMATED INCIDENCE |
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| IRRITANT-INDUCED ASTHMA (RADS) |
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| HYPERSENSITIVITY-INDUCED ASTHMA: EXPOSURERESPONSE RELATIONSHIPS |
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| OUTCOME OF OCCUPATIONAL ASTHMA |
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| PREVENTION OF OCCUPATIONAL ASTHMA |
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| OCCUPATIONAL ASTHMA: PAST AND FUTURE |
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