Ann. occup. Hyg., Vol. 48, No. 1, pp. 85, 2004
© 2004 British Occupational Hygiene Society
Published by Oxford University Press
Book Review |
Guide to Cytochrome P450 Structure and Function, David F. V. Lewis. ISBN 0748408975. Price £34.99. 215 pp.
Centre for Occupational and Environmental Health, School of Epidemiology and Health, Sciences, The University of Manchester, Humanities Building, Oxford Road, Manchester M13 9PL, UK
| The first 10% of the full text of this article appears below. |
The cytochromes P450 are an important family of xenobiotic-metabolizing enzymes, as they are believed to metabolize most foreign compounds including carcinogens and drugs. Indeed, over 200 000 chemicals are metabolized by these cytochromes and it is widely believed that differing susceptibility to chemically induced ill-health may be associated with