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Ann. occup. Hyg., Vol. 46, No. suppl_1, pp. 93-94, 2002
© 2002 British Occupational Hygiene Society
Published by Oxford University Press

Cohort Mortality Study of Vermiculite Miners Exposed to Fibrous Tremolite: An Update

J. C. McDonald1,*, J. Harris1 and B. Armstrong2

1 Department of Occupational & Environmental Medicine, National Heart & Lung Institute, Imperial College Dovehouse Street, London SW3 6LY
2 Environmental Epidemiology Unit, London School of Hygiene and Tropical Medicine, University of London Keppel Street, London WC1E 7HT, UK

*Author to whom correspondence should be addressed. Fax: +44-020-7351-8091; e-mail: c.mcdonald{at}ic.ac.uk

A further follow-up was made of a cohort of 406 American vermiculite mine workers exposed on average to 18 fibres/ml of tremolite. Total deaths to the end of 1999 were: all causes 285 (SMR 1.27), lung cancer 44 (SMR 2.40), mesothelioma 12 (PMR 4.21%). Lung cancer SMRs increased steeply with cumulative exposure (f/ml.yr). These findings show the potential magnitude of the carcinogenic effects of tremolite fibres when contaminating commercial chrysotile, and are relevant to risks associated with tremolite fibres in the general environment.

tremolite • cohort mortality • vermiculite • chrysotile


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J C McDonald, J Harris, and B Armstrong
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